Vanadium is very secure but has a weak content blocker and no fingerprinting protections.

Helium has uBlock Origin but may have canvas fingerprinting protections (inherited from ungoogled Chromium). It also inherits the security issues present in upstream ungoogled Chromium.

Cromite has an alright built-in content blocker (ABP engine) and supports adding uBlock Origin, and has decent fingerprinting protections. Cromite doesn’t have good default settings for its ABP blocklists or important anti-fingerprint settings.