The ancient Egyptians were the first to invent the toothbrush, dating back to around 5000 BC. The world’s first toothbrush was made in Egypt
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I’d like to see more non-plastic toothbrushes, personally!
Native Americans would break a twig off of a tree, chew the end until it was all splintered and soft, and use that to brush their teeth. Especially if the wood is green and fresh, the splinters will be surprisingly soft and flexible.